TGen - Research Associate I

City of Hope

Phoenix, AZ

Job posting number: #7144493 (Ref:10021462)

Posted: May 10, 2023

Application Deadline: Open Until Filled

Job Description

About TGen

TGen, the Translational Genomics Research Institute, is an affiliate of City of Hope. We are an Arizona-based, nonprofit medical research institute dedicated to conducting groundbreaking research with life-changing results. We work to unravel the genetic components of common and complex diseases, including cancer, neurological disorders, infectious disease, and rare childhood disorders. By identifying treatment options in this manner, we believe medicine becomes more rational, more precise and, well, more personal.

At TGen, we are setting a new medical standard where the future of medicine is happening now. We are pioneers in deciphering the story a person’s genome has to tell. For individuals faced with a serious diagnosis, our scientists and clinicians have the ability to let a patients’ genome reveal its uniqueness in ways that are both powerful and transformative, especially when it comes to treating disease in a precise and individual manner.

TGen has had an important and highly positive impact in understanding the molecular drivers in cancer and other diseases and disorders, but more importantly, has been among the world’s leaders in applying this knowledge toward the treatment of patients. By strategically aligning ourselves with first-in-class medical providers, TGen provides direct benefit to those patients faced with limited options.

A hallmark of TGen is our belief that by utilizing the latest technologies and collaborating with the strongest of partners, we can develop better tools to increase our understanding of complex diseases and to better predict which treatments might be most effective, i.e., one-of-a-kind clinical trials (the right drug, at the right dose, at the right time).

TGen’s translational approach and our experience at leveraging genomic information in support of achieving more precise and personalized treatments augments your work in ways other institutes cannot. Our affiliation with City of Hope allows you to integrate your work with a growing health system committed to research with highest potential for improvements in patient care. In short, our science-led business-supported approach means there’s no better place to move your research forward. If you’re looking for a job with purpose, you’ll find it at TGen.

Position Summary

TGen's Collaborative Sequencing Center (CSC) is the primary next generation sequencing resource for internal and external investigators and our goal is to help expedite translational research on cancers and neurological diseases. The CSC provides a variety of services from DNA and RNA isolation, sequencing library construction, and sequencing on a variety of Illumina and Oxford Nanopore platforms.

The CSC is looking for a motivated, organized, and detail-oriented individual to participate in the completion of collaborative sequencing projects. Completion of projects can involve manual or robotic nucleic acid extractions, sequencing library preparation, loading and maintaining sequencing instruments, detailed record-keeping using a laboratory information management system, evaluation of pre- and post-sequencing quality control metrics.

Duties and Responsibilities

Requirements will include a range of molecular biology techniques, operation of standard lab equipment and sequencing instruments. This person will need to communicate effectively with all levels of staff to ensure that data integrity and team goals are met and will need to be comfortable with multitasking.

Responsibilities will focus on the sequencing technology, which is heavily reliant on being skilled in the lab and having excellent problem solving/reasoning skills.

· Generate data for research and experimental purposes following established research procedures.

· Develop and optimize assays for sequencing applications and perform detailed documentation.

· Perform troubleshooting and maintenance on laboratory equipment.

· Work closely with lab director, lab manager, CSC lab staff, informatics staff, field service engineers, and instrument technical service specialists when needed.

· Perform general laboratory duties.

· Research literature related to projects as needed.

· Assist in safety and lab equipment training, protocols, data analysis, and presentations.

· Participate in lab meetings by updating lab of progress, results, and future goals/studies.

· Mentor interns and graduate students.

Basic education, experience and skills required for consideration:

· Bachelor's Degree in a science-related field (Biology, Molecular and Cellular Biology, Genetics) is required with 1 year working experience in a lab after graduation is preferred.

· Strong communication skills, the ability to read and write scientifically, excellent organization and record-keeping skills, and critical thinking skills are needed.

· Requires familiarity with a variety of the field's concepts, practices, and procedures and experience with standard laboratory equipment.

· Clear experience in molecular biology techniques is a requirement.

· Experience with next-generation sequencing methods is not required but would be a strong asset for an applicant.

· Must be comfortable using Microsoft Office products or comparable software.

· Special consideration will be given to applicants with prior experience in a sequencing lab or high-throughput laboratories.

· Candidate should be independent enough to manage his/her own projects once properly trained. Candidate will be responsible for planning, execution, QC analysis of study and communication with other groups involved in study. This candidate will also be responsible for training of others.

To Apply please click the link below:

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.

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More Info

Job posting number:#7144493 (Ref:10021462)
Application Deadline:Open Until Filled
Employer Location:City of Hope
United States
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